GlycoEra employs in-depth knowledge of engineering complex carbohydrate structures and is at the forefront of developing novel therapeutics targeting degradation of circulating and membrane proteins that cause disease. GlycoEra’s CustomGlycan Platform is the only cell-based technology offering unparalleled, controlled glycan structure design capabilities, enabling several glycan-mediated functions. This opens a new era in developing novel drugs.
Our understanding of the biology mediated by glycans, and their receptors are quickly evolving due to the rapid advances in technologies. Recent studies demonstrate that glycans play predominant roles in protein trafficking, immune regulation, and cell functions. Glycans enable unique functions by engaging different carbohydrate-binding receptors to induce diverse pathways including targeting to cellular compartments, scavenging of unique glycan structures, stimulating immune cells, and signaling. Hence, designing and controlling the glycan that is displayed on a recombinant protein using CustomGlycan platform enables you to leverage glycan pathways for specific purposes, like targeted degradation of circulating and membrane proteins.